Actualités

1. J Proteome Res. 2013 Aug 2;12(8):3746-54. Metabolomics in cerebrospinal fluid of patients with amyotrophic lateral sclerosis: an untargeted approach via high-resolution mass spectrometry. Blasco H1, Corcia P, Pradat PF, Bocca C, Gordon PH, Veyrat-Durebex C, Mavel S, Nadal-Desbarats L, Moreau C, Devos D, Andres CR, Emond P.

2. Am J Physiol Regul Integr Comp Physiol. 2012 Jul 15;303(2):R135-43. Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone. Wolowczuk I, Hennart B, Leloire A, Bessede A, Soichot M, Taront S, Caiazzo R, Raverdy V, Pigeyre M; ABOS Consortium, Guillemin GJ, Allorge D, Pattou F, Froguel P, Poulain-Godefroy O.

3. Diabetologia. 2014 Jan 26. Alternative human liver transcripts of TCF7L2 bind to the gluconeogenesis regulator HNF4α at the protein level.Neve B1, Le Bacquer O, Caron S, Huyvaert M, Leloire A, Poulain-Godefroy O, Lecoeur C, Pattou F, Staels B, Froguel P.

4. Biochim Biophys Acta. 2014 Apr;1842(4):584-93.Adipose Tissue Macrophages (ATM) of obese patients are releasing increased levels of prolactin during an inflammatory challenge: A role for prolactin in diabesity? Bouckenooghe T, Sisino G, Aurientis S, Chinetti-Gbaguidi G, Kerr-Conte J, Staels B, Fontaine P, Storme L, Pattou F, Vambergue A.

5. Eur Heart J. 2013 Aug;34(32):2566-74. doi: 10.1093/eurheartj/ehs227. Epub 2012 Jul 26. Activation of intestinal peroxisome proliferator-activated receptor-α increases high-density lipoprotein production. Colin S1, Briand O, Touche V, Wouters K, Baron M, Pattou F, Hanf R, Tailleux A, Chinetti G, Staels B, Lestavel S.

6. Am J Physiol Regul Integr Comp Physiol. 2012 Jul 15;303(2):R135-43. doi: 10.1152/ajpregu.00373.2011. Tryptophan metabolism activation by indoleamine 2,3-dioxygenase in adipose tissue of obese women: an attempt to maintain immune homeostasis and vascular tone. Wolowczuk I1, Hennart B, Leloire A, Bessede A, Soichot M, Taront S, Caiazzo R, Raverdy V, Pigeyre M; ABOS Consortium, Guillemin GJ, Allorge D, Pattou F, Froguel P, Poulain-Godefroy O.

7. J Biol Chem. 2012 Jun 22;287(26):21904-13. Human adipose tissue macrophages display activation of cancer-related pathways. Mayi TH1, Daoudi M, Derudas B, Gross B, Bories G, Wouters K, Brozek J, Caiazzo R, Raverdi V, Pigeyre M, Allavena P, Mantovani A, Pattou F, Staels B, Chinetti-Gbaguidi G.

8. Nature. 2012 Feb 19;483(7389):350-4. Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Ichimura A1, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Körner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Lévy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, Froguel P.

9. Diab Vasc Dis Res. 2012 Jul;9(3):189-95. doi: 10.1177/1479164111430242. Epub 2011 Dec 22. Impaired alternative macrophage differentiation of peripheral blood mononuclear cells from obese subjects. Bories G1, Caiazzo R, Derudas B, Copin C, Raverdy V, Pigeyre M, Pattou F, Staels B, Chinetti-Gbaguidi G.

10. Diabetologia. 2011 Dec;54(12):3150-6. Downregulation of the tumour suppressor p16INK4A contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype. Fuentes L1, Wouters K, Hannou SA, Cudejko C, Rigamonti E, Mayi TH, Derudas B, Pattou F, Chinetti-Gbaguidi G, Staels B, Paumelle R.

11. Gastroenterology. 2011 May;140(5):1564-74. PPARβ/δ activation induces enteroendocrine L cell GLP-1 production. Daoudi M1, Hennuyer N, Borland MG, Touche V, Duhem C, Gross B, Caiazzo R, Kerr-Conte J, Pattou F, Peters JM, Staels B, Lestavel S.

12. Biochem Biophys Res Commun. 2011 Jan 7;404(1):458-62. Liver X Receptor (LXR) activation negatively regulates visfatin expression in macrophages. Mayi TH1, Rigamonti E, Pattou F, Staels B, Chinetti-Gbaguidi G.

13. FEBS J. 2010 Aug;277(16):3308-20. Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages. Mayi TH1, Duhem C, Copin C, Bouhlel MA, Rigamonti E, Pattou F, Staels B, Chinetti-Gbaguidi G.

14. J Clin Invest. 2010 May;120(5):1454-68 Proteasomal degradation of retinoid X receptor alpha reprograms transcriptional activity of PPARgamma in obese mice and humans. Lefebvre B1, Benomar Y, Guédin A, Langlois A, Hennuyer N, Dumont J, Bouchaert E, Dacquet C, Pénicaud L, Casteilla L, Pattou F, Ktorza A, Staels B, Lefebvre P.

15. Mediators Inflamm. 2010;2010:823486.. Inflammatory role of Toll-like receptors in human and murine adipose tissue. Poulain-Godefroy O1, Le Bacquer O, Plancq P, Lecoeur C, Pattou F, Frühbeck G, Froguel P.

16. Am J Physiol Regul Integr Comp Physiol. 2008 Jul;295(1):R1-7. Inflammation is associated with a decrease of lipogenic factors in omental fat in women. Poulain-Godefroy O1, Lecoeur C, Pattou F, Frühbeck G, Froguel P.

17. Ann Neurol. 2008 Jun;63(6):743-50. Genomic investigation of alpha-synuclein multiplication and parkinsonism. Ross OA1, Braithwaite AT, Skipper LM, Kachergus J, Hulihan MM, Middleton FA, Nishioka K, Fuchs J, Gasser T, Maraganore DM, Adler CH, Larvor L, Chartier-Harlin MC, Nilsson C, Langston JW, Gwinn K, Hattori N, Farrer MJ.

18. Neurobiol Aging. 2011 Mar;32(3):548.e9-18. A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease. Krüger R1, Sharma M, Riess O, Gasser T, Van Broeckhoven C, Theuns J, Aasly J, Annesi G, Bentivoglio AR, Brice A, Djarmati A, Elbaz A, Farrer M, Ferrarese C, Gibson JM, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Klein C, Lambert JC, Lesage S, Lin JJ, Lynch T, Mellick GD, de Nigris F, Opala G, Prigione A, Quattrone A, Ross OA, Satake W, Silburn PA, Tan EK, Toda T, Tomiyama H, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM; Genetic Epidemiology of Parkinson's disease consortium.

19. Neurobiol Aging. 2011 Oct;32(10):1839-48.Transcriptional profile of Parkinson blood mononuclear cells with LRRK2 mutation. Mutez E, Larvor L, Leprêtre F, Mouroux V, Hamalek D, Kerckaert JP, Pérez-Tur J, Waucquier N, Vanbesien-Mailliot C, Duflot A, Devos D, Defebvre L, Kreisler A, Frigard B, Destée A, Chartier-Harlin MC.

20. Neurobiol Dis. 2014 Mar;63:165-70. Involvement of the immune system, endocytosis and EIF2 signaling in both genetically determined and sporadic forms of Parkinson's disease. Mutez E, Nkiliza A, Belarbi K, de Broucker A, Vanbesien-Mailliot C, Bleuse S, Duflot A, Comptdaer T, Semaille P, Blervaque R, Hot D, Leprêtre F, Figeac M, Destée A, Chartier-Harlin MC.

21. Biochim Biophys Acta. 2013 Dec;1832(12):1959-68.Diabetes during pregnancy influences Hofbauer cells, a subtype of placental macrophages, to acquire a pro-inflammatory phenotype. Sisino G, Bouckenooghe T, Aurientis S, Fontaine P, Storme L, Vambergue A.

22. Placenta. 2010 Sep;31(9):785-91. Placental BDNF/TrkB signaling system is modulated by fetal growth disturbances in rat and human. Mayeur S1, Silhol M, Moitrot E, Barbaux S, Breton C, Gabory A, Vaiman D, Dutriez-Casteloot I, Fajardy I, Vambergue A, Tapia-Arancibia L, Bastide B, Storme L, Junien C, Vieau D, Lesage J.

23. BMC Mol Biol. 2009 Mar 10;10:21.Time course analysis of RNA stability in human placenta. Fajardy I, Moitrot E, Vambergue A, Vandersippe-Millot M, Deruelle P, Rousseaux J.

24. Cardiovasc Revasc Med. 2009 Jul-Sep;10(3):144-50. Preprocedural high-sensitivity C-reactive protein predicts death or myocardial infarction but not target vessel revascularization or stent thrombosis after percutaneous coronary intervention. Delhaye C, Sudre A, Lemesle G, Maréchaux S, Broucqsault D, Hennache B, Bauters C, Lablanche JM.

25. Am J Gastroenterol. 2013 Oct;108(10):1647-53. Mortality and cancer in pediatric-onset inflammatory bowel disease: a population-based study. Peneau A, Savoye G, Turck D, Dauchet L, Fumery M, Salleron J, Lerebours E, Ligier K, Vasseur F, Dupas JL, Mouterde O, Spyckerelle C, Djeddi D, Peyrin-Biroulet L, Colombel JF, Gower-Rousseau C.

26. BMC Med Genet. 2013 Mar 18;14:35. The CARD8 p.C10X mutation associates with a low anti-glycans antibody response in patients with Crohn's disease. Vasseur F1, Sendid B, Broly F, Gower-Rousseau C, Sarazin A, Standaert-Vitse A, Colombel JF, Poulain D, Jouault T.

27. Gut. 2014 Mar;63(3):423-32. Natural history of elderly-onset inflammatory bowel disease: a population-based cohort study.Charpentier C1, Salleron J, Savoye G, Fumery M, Merle V, Laberenne JE, Vasseur F, Dupas JL, Cortot A, Dauchet L, Peyrin-Biroulet L, Lerebours E, Colombel JF, Gower-Rousseau C.

28. Dig Liver Dis. 2013 Feb;45(2):89-94. Epidemiology of inflammatory bowel diseases: new insights from a French population-based registry (EPIMAD).Gower-Rousseau C1, Vasseur F, Fumery M, Savoye G, Salleron J, Dauchet L, Turck D, Cortot A, Peyrin-Biroulet L, Colombel JF.

29. Inflamm Bowel Dis. 2012 Mar;18(3):430-8. Variants of NOD1 and NOD2 genes display opposite associations with familial risk of Crohn's disease and anti-saccharomyces cerevisiae antibody levels.Vasseur F1, Sendid B, Jouault T, Standaert-Vitse A, Dubuquoy L, Francois N, Gower-Rousseau C, Desreumaux P, Broly F, Vermeire S, Colombel JF, Poulain D.

30. Inflamm Bowel Dis. 2010 Jan;16(1):58-67. Familial aggregation and antimicrobial response dose-dependently affect the risk for Crohn's disease. Joossens M1, Van Steen K, Branche J, Sendid B, Rutgeerts P, Vasseur F, Poulain D, Broly F, Colombel JF, Vermeire S, Chamaillard M.

31. Am J Gastroenterol. 2009 Jul;104(7):1745-53.Candida albicans colonization and ASCA in familial Crohn's disease. Standaert-Vitse A, Sendid B, Joossens M, François N, Vandewalle-El Khoury P, Branche J, Van Kruiningen H, Jouault T, Rutgeerts P, Gower-Rousseau C, Libersa C, Neut C, Broly F, Chamaillard M, Vermeire S, Poulain D, Colombel JF.

32. PLoS Genet. 2013;9(9).Deep resequencing of GWAS loci identifies rare variants in CARD9, IL23R and RNF186 that are associated with ulcerative colitis. Beaudoin M1, Goyette P, Boucher G, Lo KS, Rivas MA, Stevens C, Alikashani A, Ladouceur M, Ellinghaus D, Törkvist L, Goel G, Lagacé C, Annese V, Bitton A, Begun J, Brant SR, Bresso F, Cho JH, Duerr RH, Halfvarson J, McGovern DP, Radford-Smith G, Schreiber S, Schumm PL, Sharma Y, Silverberg MS, Weersma RK; Quebec IBD Genetics Consortium; NIDDK IBD Genetics Consortium; International IBD Genetics Consortium, D'Amato M, Vermeire S, Franke A, Lettre G, Xavier RJ, Daly MJ, Rioux JD.

33. Medicine (Baltimore). 2013 Aug 26. The Spectrum of FIP1L1-PDGFRA-Associated Chronic Eosinophilic Leukemia: New Insights Based on a Survey of 44 Cases.Legrand F1, Renneville A, Macintyre E, Mastrilli S, Ackermann F, Cayuela JM, Rousselot P, Schmidt-Tanguy A, Fain O, Michel M, de Jaureguiberry JP, Hatron PY, Cony-Makhoul P, Lefranc D, Sène D, Cottin V, Hamidou M, Lidove O, Baruchel A, Dubucquoi S, Bletry O, Preudhomme C, Capron M, Prin L, Kahn JE; on behalf of the French Eosinophil Network.

34. J Proteome Res. 2011 Apr 1;10(4):1468-80. Comparative proteomic analysis of blood eosinophils reveals redox signaling modifications in patients with FIP1L1-PDGFRA-associated chronic eosinophilic leukemia. Kahn JE, Dutoit-Lefevre V, Duban-Deweer S, Chafey P, Pottiez G, Lefranc D, Fain O, Cordier JF, Hatron PY, Bletry O, Prin L.

35. J Toxicol Environ Health A. 2013;76(15):895-906. Influence of delta-aminolevulinic acid dehydratase gene polymorphism on selected lead exposure biomarkers in a cohort of ex-smelter workers. Leroyer A, Leleu B, Dehon B, Frimat P, Broly F, Nisse C.

36. Sci Total Environ. 2010 Feb 1;408(5):1166-73. 1-Hydroxypyrene and 3-hydroxybenzo[a]pyrene as biomarkers of exposure to PAH in various environmental exposure situations. Leroyer A, Jeandel F, Maitre A, Howsam M, Deplanque D, Mazzuca M, Nisse C.

37. PLoS One. 2012;7(12):e52223. doi: 10.1371/journal.pone.0052223. Epub 2012 Dec 27. Genotype/phenotype analyses for 53 Crohn's disease associated genetic polymorphisms. Jung C, Colombel JF, Lemann M, Beaugerie L, Allez M, Cosnes J, Vernier-Massouille G, Gornet JM, Gendre JP, Cezard JP, Ruemmele FM, Turck D, Merlin F, Zouali H, Libersa C, Dieudé P, Soufir N, Thomas G, Hugot JP.

38. J Proteome Res. 2013 Aug 2;12(8):3746-54. Metabolomics in cerebrospinal fluid of patients with amyotrophic lateral sclerosis: an untargeted approach via high-resolution mass spectrometry. Blasco H1, Corcia P, Pradat PF, Bocca C, Gordon PH, Veyrat-Durebex C, Mavel S, Nadal-Desbarats L, Moreau C, Devos D, Andres CR, Emond P.

39. J Neurol. 2013 Apr;260(4):998-1003. MBNL1 gene variants as modifiers of disease severity in myotonic dystrophy type 1. Huin V1, Vasseur F, Schraen-Maschke S, Dhaenens CM, Devos P, Dupont K, Sergeant N, Buée L, Lacour A, Hofmann-Radvanyi H, Sablonnière B.

40. Exp Neurol. 2008 Apr;210(2):467-78. Overexpression of MBNL1 fetal isoforms and modified splicing of Tau in the DM1 brain: two individual consequences of CUG trinucleotide repeats. Dhaenens CM, Schraen-Maschke S, Tran H, Vingtdeux V, Ghanem D, Leroy O, Delplanque J, Vanbrussel E, Delacourte A, Vermersch P, Maurage CA, Gruffat H, Sergeant A, Mahadevan MS, Ishiura S, Buée L, Cooper TA, Caillet-Boudin ML, Charlet-Berguerand N, Sablonnière B, Sergeant N.